APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death
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چکیده
منابع مشابه
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death
p53 is a transcriptional activator which has been implicated as a key regulator of neuronal cell death after acute injury. We have shown previously that p53-mediated neuronal cell death involves a Bax-dependent activation of caspase 3; however, the transcriptional targets involved in the regulation of this process have not been identified. In the present study, we demonstrate that p53 directly ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2001
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200105137